
× ×ª×× × ×ª×¨×פ×
××רש×

| ×§×××¦× ×¤×¨××§×××××ת (ATC4)
|
C10AX Other lipid modifying agents
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| ×ר××× ×¤×¢×× (ATC5)
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Â
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| צ×רת ×ת×
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תת-×¢××¨× - S.C
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| צ×רת ××× ××
|
ת×××¡× ×××רק×, SOLUTION FOR INJECTION ××× ×עת ××× ×× ×תר ×× ×רע×× ×ש ××××× ×ת ×תר××¤× ××ת×× ×××× ×× ××××××¥ ××¤× ×©××פ××¢ ××¢××× ×צר××
|
| ×ת××××
|
Hypercholesterolaemia and mixed dyslipidaemiaRepatha is indicated in adults with primary hypercholesterolaemia (heterozygous familial and non familial) or mixed dyslipidaemia, as an adjunct to diet:⢠in combination with a statin or statin with other lipid lowering therapies in patients unable to reach LDL-C goals with the maximum tolerated dose of a statin or,⢠alone or in combination with other lipid-lowering therapies in patients who are statin-intolerant, or for whom a statin is contraindicated.Homozygous familial hypercholesterolaemiaRepatha is indicated in adults and adolescents aged 12 years and over with homozygous familial hypercholesterolaemia in combination with other lipid-lowering therapies.Established atherosclerotic cardiovascular diseaseRepatha is indicated in adults with established atherosclerotic cardiovascular disease (myocardial infraction, stroke or peripheral arterial disease) to reduce cardiovascular risk by lowering LDL-C levels, as an adjunct to correction of other risk factors:⢠in combination with the maximum tolerated dose of a statin with or without other lipid lowering therapies or,⢠alone or in combination with other lipid-lowering therapies in patients who are statin-intolerant, or for whom a statin is contraindicated.
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| × ×ª×× × ×ס×
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ת×ר×× ××××× ×ס×
- 21/01/2016
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×××××ת ×ס×
- תר××¤× ×××××ת ×ר×ש×× ×¢'× ×¨××¤× ××××× ×× ××××× ××רת
|
×ת×××× ×ס×
| ×ת×××× |
ת×ר×× ××××× |
ת××× ×§××× × |
Class Effect |
××¦× ×××× |
×ס×ס ×××××ת
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| ×. ×× ××¢× ×©× ××× ×ת ×©× ××ר××¢×× ×§×¨××××סק××ר××× ×××××× ×¢× ×××× ×§×¨××××סק××ר×ת ××××¢× ×©××× ×××× ×©×¨×ר ××× ×× ×©××¥ ×××× ××ס××× ×× ×××××× ×ש××ש ××©× ×× ××¨× ××ער×× ×ער×× ×-LDL ש××× ××¢× 130 ×"×/×צ"×, ××ר×ת ××פ×× ×ר×× ×ס×××× ×× ×ש×××× ×¢× Ezetimibe, ×××©× ×××ש××× ×פ××ת. ×. ×ת××ת ×××פ×× ×תר××¤× ×××¢×©× ××¤× ××¨×©× ×©× ×¨××¤× ××××× ×קר×××××××× ×× ×¨××¤× ××××× ×××פ××××.
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11/01/2018
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××פ×××× |
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××פר×××ס×ר×××××, ××ס××פ××××× |
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| ××פ×× ×××פר×××ס×ר××××× ××××× ×ס××× ×-Homozygous familial hypercholesterolemia ×××ר ××צ×× ××פ×× ×©× ×¡×××× ×× ×¢× Ezetimibe. ×ת××ת ×××פ×× ×תר××¤× ×××¢×©× ××¤× ××¨×©× ×©× ×¨××¤× ××××× ×××פ××××
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21/01/2016
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××פ×××× |
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××פר×××ס×ר××××× ×שפ×ת×ת ××××××××××ת |
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| ×. ×× ××¢× ×©× ××× ×ת ×©× ××ר××¢×× ×§×¨××××סק××ר××× ×××××× ×¢× ×××× ×§×¨××××סק××ר×ת ××××¢× ×©××× ××¢×ר ×××× ×©×¨×ר ××× ×× ×©××¥ ×××× ××ס××× ×× ×××××× ×ער×× ×-LDL ש××× ××¢× 100 ×"×/×צ"×, ××ר×ת ××פ×× ×ר×× ×ס×××× ×× ×ש×××× ×¢× Ezetimibe, ×××©× ×××ש××× ×פ××ת. ×.×ת××ת ×××פ×× ×תר××¤× ×××¢×©× ××¤× ××¨×©× ×©× ×¨××¤× ××××× ×קר×××××××× ×× ×¨××¤× ××××× ×××פ×××× ×× ×¨××¤× ××××× ×× ××ר××××××.
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01/02/2023
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××פ××××
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EVOLOCUMAB, ALIROCUMAB
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××פר×××ס×ר×××××, ××ס××פ××××× |
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| ×× ××¢× ×©× ××× ×ת ×©× ××ר××¢×× ×§×¨××××סק××ר××× ×××××× ×¢× ×××× ×§×¨××××סק××ר×ת ××××¢× ×©××× ×××× ×©×¨×ר ××× ×× ×©××¥ ×××× ××ס××× ×× ×××××× ×ש××ש ××©× ×× ××¨× ××ער×× ×ער×× ×-LDL ש××× ××¢× 100 ×"×/×צ"×, ××ר×ת ××פ×× ×ר×× ×ס×××× ×× ×ש×××× ×¢× Ezetimibe, ×××©× ×××ש××× ×פ××ת. ×. ×ת××ת ×××פ×× ×תר××¤× ×××¢×©× ××¤× ××¨×©× ×©× ×¨××¤× ××××× ×קר×××××××× ×× ×¨××¤× ××××× ×××פ×××× ×× ×¨××¤× ××××× ×× ××ר××××××.
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30/01/2020
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××פ×××× |
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××פר×××ס×ר×××××, ××ס××פ××××× |
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| ××פ×× ×××פר×××ס×ר××××× ××××× ×ס××× ×-Homozygous familial hypercholesterolemia ×××ר ××צ×× ××פ×× ×©× ×¡×××× ×× ×¢× Ezetimibe. ×ת××ת ×××פ×× ×תר××¤× ×××¢×©× ××¤× ××¨×©× ×©× ×¨××¤× ××××× ×קר×××××××× ×× ×¨××¤× ××××× ×××פ××××
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11/01/2018
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××פ×××× |
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××פר×××ס×ר××××× ×שפ×ת×ת ××××××××××ת |
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ש×××ש ×ס×
-
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×ס×רת ××××× ×ס×
- ×. ×תר××¤× ×ª×× ×ª× ×××פ×× ××קר×× ××××:
- 1. ××פ×× ×××פר×××ס×ר××××× ××××× ×ס××× ×-Homozygous familial hypercholesterolemia ×××ר ××צ×× ××פ×× ×©× ×¡×××× ×× ×¢× Ezetimibe.
- 2. ×× ××¢× ×©× ××× ×ת ×©× ××ר××¢×× ×§×¨××××סק××ר××× ×××××× ×¢× ×××× ×§×¨××××סק××ר×ת ××××¢× ×©××× ××¢×ר ×××× ×©×¨×ר ××× ×× ×©××¥ ×××× ××ס××× ×× ×××××× ×ער×× ×-LDL ש××× ××¢× 100 ×"×/×צ"×, ××ר×ת ××פ×× ×ר×× ×ס×××× ×× ×ש×××× ×¢× Ezetimibe, ×××©× ×××ש××× ×פ××ת.
- ×.×ת××ת ×××פ×× ×תר××¤× ×××¢×©× ××¤× ××¨×©× ×©× ×¨××¤× ××××× ×קר×××××××× ×× ×¨××¤× ××××× ×××פ×××× ×× ×¨××¤× ××××× ×× ××ר××××××.
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| ×¢××× ×ר××¤× ××××ר×ת ××¢×××
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ת××× ×ª ×ר×××
ת×ר×× ×¢××××: 14/05/2024
AMGEN
רפ××× - Repatha
true
השינוי האחרון נעשה בֹ־31 במרץ 2016 ב־21:59